
Hartley et al. comfirms mRNA ‘IMMUNE TOLERANCE’ (& IgG4 ‘class-switch’ by Irrgang et al.): “Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by
IgG4 class switch means you become more susceptible to severe illness as there is a declining immune response via traditional vaccine induced antibodies. Did Irrgang also show this? Yes! IgG4 ‘class switch’ (Irrgang et al.) toward noninflammatory, spike-specific IgG4 antibodies after