This week beginning on the evening of June 11 and ending on June 13, Shavuot the Jewish Festival of Weeks, celebrates the harvest of first fruits and commemorates the giving of the Torah and Commandments at Mount Sinai. The release of four Israeli hostages by the IDF in Gaza enhances our celebration and appreciation of our faith and legacy.
Michael Ordman’s weekly posting enhances our appreciation of present-day Israel, whose contributions and innovations in medicine, science, technology, evolve 24/7 to benefit humanity.
Happy “Shvues” as we pronounced it in the Bronx to all who observe. rsk
ISRAEL’S MEDICAL ACHIEVEMENTS
Penetrating the BBB. The nano-platform technology of Israel’s NanoCarry traverses the Blood Brain Barrier (BBB) to deliver potentially life-saving therapies to the brain. Its initial target is HER2 breast cancer brain metastases for which there is no treatment, even though the original cancer can now effectively be cured.
Penetrating Brain’s Natural Barrier To Deliver Life-Saving Drugs
Predicting what cancer cells will do next. Researchers at the Hebrew University of Jerusalem analyze cancer patient biopsies and use AI to predict disease progression or chemotherapy resistance. Using the science of nano-informatics, they expose cells to nano particles, record absorption levels, and model cellular behavior.
https://www.israel21c.org/scientists-use-ai-to-predict-what-cancer-cells-will-do-next/
https://www.science.org/doi/10.1126/sciadv.adj4370
Sickle cell disease treatment trial. Israel’s BiolineRX is to conduct Phase 1 clinical trials on sickle cell disease (SCD) patients at multiple locations in the US. It will use its motixafortide stem cell therapy (see here previously), currently used to treat multiple myeloma. SCD is caused by a mutation of the hemoglobin gene.
Israeli Biopharma Firm Leading US Trial Of Potential SCD Drug
The long road. Back in 2015 (see here previously) Israel’s Ben Gurion University researchers discovered the link between protein macrophage migration inhibitory factor (MIF) and Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. Now they are leading an international team to use it as a potential cure.
Israeli-led Study Discovers Protein’s Potential As ALS Treatment
The right antibiotic in 90 mins. Scientists at Israel’s Technion Institute have developed optical sensor technology that can identify the correct antibiotic for urinary tract and other infections in just 90 minutes. They worked with Technion alumni in a Maryland USA company and at John Hopkins University.
https://ats.org/our-impact/new-device-rapidly-identifies-exact-antibiotic-needed-for-infections/
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202303285
An ambucar needed for Netanya. Israel’s United Hatzalah is appealing for funds to purchase a rapid response vehicle – known as a minilance (mini ambulance) ATV (all-terrain vehicle). It can bring a team of up to five UH volunteers and veteran lifesaving medics to the scene of a local emergency within minutes.
https://israelrescue.org/mymitzvah/minilance-a-rapid-response-vehicle-for-netanya/
Eradicating the last polio virus. Ben-Gurion University has received a $1.3 million grant from the Gates Foundation to develop and validate a novel and safe approach for measuring immune responses to polioviruses.
https://provaeducation.com/news/ben-gurion-university-scientist-to-contribute-to-the-eradication-of-polio/2466922/ https://www.bgu.ac.il/en/news-and-articles/hertz-gates-foundation-grant/
Merck boost for antibody design startup. Israel’s Biolojic Design (see here previously) is partnering Merck, to develop molecules that could be the basis for therapies to treat cancer and other immunological disorders. The venture is potentially worth up to 350 million euros to the Israeli company.
https://www.calcalistech.com/ctechnews/article/bybenkovr
Treating late life depression. (TY Atid-EDI) The US FDA has extended its approval of the Deep Transcranial Magnetic Stimulation system from Israel’s BrainsWay (see here previously). It can now be used to treat depression up to the patient’s 86th birthday. The previous maximum age limit was 67.
BrainsWay Receives Expanded FDA Labeling to Treat Late Life Depression
Exercises restore eyesight. Israel’s RevitalVision (see here previously) has been very successful in improving the condition of the visually impaired. On average, the structured on-line brain exercises achieve a measurable improvement of 20 – 25%, equivalent to an extra two lines on a standard eye chart.
https://www.israel21c.org/improving-vision-with-at-home-brain-exercises/
Watch out for snakes. Doctors saved an Israeli woman in her 50s after she was bitten by a snake in southern Israel. She was brought to Ashdod hospital by family members who also brought the snake. Doctors were able to identify the snake and administer the correct anti-venom serum. The article contains some important advice.
https://www.israelnationalnews.com/news/390948
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Author: Ruth King
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