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In other words, this study found that in young adults (mean age = 27.2), mRNA injection likely leads to sustained Spike protein production lasting at least one year—evidenced by persistently elevated levels of multiple proinflammatory cytokines.
Key Points from the Study:
Long-Term Immune Stimulation
Participants showed significantly elevated cytokine levels 13–14 months post-vaccination, well beyond the expected duration of a typical immune response.
Cytokines Upregulated After mRNA Injection
TNF-α, IL-1β, IL-6, IL-4, IL-7, IL-17E
These cytokines are associated with chronic inflammation, immune dysregulation, and autoimmune activation.
VEGFA (angiogenesis), FGF2, IFN-γ
These markers are linked to vascular remodeling, tissue repair, and persistent immune activation.
MCP-1, MCP-3
These markers are associated with chronic inflammation, vascular remodeling, and autoimmunity.
Only One Cytokine Decreased
Macrophage colony-stimulating factor (MCSF) levels dropped significantly, possibly indicating immune system dysregulation.
Mechanistic Implication
The authors suggest this sustained cytokine activity may stem from the persistent expression of Spike protein, driven by:
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Modified nucleoside-stabilized mRNA
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Pro-inflammatory lipid nanoparticles known for systemic biodistribution
Biological and Clinical Concerns
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Prolonged IL-6 and TNF-α elevation is linked to autoimmune conditions and post-acute inflammatory syndromes.
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Persistent VEGFA suggests ongoing vascular endothelial activation and potential long-term cardiovascular effects.
These findings are not unexpected — 130 peer reviewed studies have documented:
I) the systemic biodistribution of the injected mRNA,
II) the persistence of both the synthetic mRNA and the spike protein it encodes, and
III) the toxic potential of the lipid nanoparticle (LNP) delivery system used to transport the genetic payload.
As yet another study reveals grave harms linked to the COVID-19 mRNA injections, the case for their immediate removal from the market grows stronger and more urgent.
Epidemiologist and Foundation Administrator, McCullough Foundation
www.mcculloughfnd.org
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